Tjip S van der Werf Selected Research

Isoniazid (Ftivazide)

1/2022	Clinical Relevance of Rifampicin-Moxifloxacin Interaction in Isoniazid-Resistant/Intolerant Tuberculosis Patients.
10/2020	Dose optimisation of first-line tuberculosis drugs using therapeutic drug monitoring in saliva: feasible for rifampicin, not for isoniazid.
1/2019	A Systematic Review on the Effect of HIV Infection on the Pharmacokinetics of First-Line Tuberculosis Drugs.
11/2018	Intermediate Susceptibility Dose-Dependent Breakpoints For High-Dose Rifampin, Isoniazid, and Pyrazinamide Treatment in Multidrug-Resistant Tuberculosis Programs.
1/2018	Treatment and outcomes in children with multidrug-resistant tuberculosis: A systematic review and individual patient data meta-analysis.
10/2016	Dosage of isoniazid and rifampicin poorly predicts drug exposure in tuberculosis patients.
8/2015	Pharmacokinetic Modeling and Optimal Sampling Strategies for Therapeutic Drug Monitoring of Rifampin in Patients with Tuberculosis.

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Tjip S van der Werf Research Topics

Disease

32	Tuberculosis (Tuberculoses) 12/2023 - 03/2004
20	Multidrug-Resistant Tuberculosis (Drug-Resistant Tuberculosis) 12/2023 - 02/2010
15	Buruli Ulcer 01/2020 - 06/2003
11	Infections 03/2019 - 09/2004
5	Inflammation (Inflammations) 04/2023 - 12/2014
5	Extensively Drug-Resistant Tuberculosis 01/2019 - 08/2010
4	Critical Illness (Critically Ill) 01/2020 - 01/2014
4	Mycoses (Diseases, Fungus) 08/2019 - 10/2013
4	Ulcer 01/2018 - 09/2003
3	Chronic Obstructive Pulmonary Disease (COPD) 04/2022 - 01/2019
3	Body Weight (Weight, Body) 01/2020 - 12/2014
3	Pain (Aches) 12/2016 - 01/2015
3	Pneumonia (Pneumonitis) 07/2012 - 05/2010
2	Aspergillosis 02/2023 - 08/2019
2	Vomiting 01/2022 - 12/2015
2	Pulmonary Tuberculosis 08/2020 - 01/2019
2	HIV Infections (HIV Infection) 01/2019 - 01/2017
2	Thrombocytopenia (Thrombopenia) 06/2017 - 02/2010
2	Wounds and Injuries (Trauma) 12/2016 - 01/2015
2	Bronchiectasis 01/2016 - 03/2013
2	Cystic Fibrosis (Mucoviscidosis) 01/2016 - 03/2013
2	Peripheral Nervous System Diseases (PNS Diseases) 08/2010 - 02/2010
2	Human Influenza (Influenza) 03/2010 - 10/2008
2	Necrosis 09/2003 - 06/2003
1	Invasive Fungal Infections 04/2023
1	Drug-Related Side Effects and Adverse Reactions 02/2023
1	Mucositis 02/2023
1	Nausea 01/2022
1	Cicatrix (Scar) 01/2020
1	Opportunistic Infections (Opportunistic Infection) 01/2020
1	Breakthrough Infections 01/2020
1	Overweight 01/2020
1	Granuloma 12/2019
1	Fistula 01/2018
1	Eosinophilia 10/2017
1	Hepatic Encephalopathy 03/2017
1	Burns 01/2017
1	Hypertension (High Blood Pressure) 01/2017
1	Chronic Renal Insufficiency 01/2017
1	Diabetes Mellitus 01/2017
1	Rupture 01/2017
1	Bites and Stings (Sting) 01/2017

Drug/Important Bio-Agent (IBA)

16	Rifampin (Rifampicin)FDA LinkGeneric 12/2023 - 09/2003
12	Anti-Bacterial Agents (Antibiotics)IBA 10/2019 - 07/2009
9	Linezolid (Zyvox)FDA Link 12/2019 - 02/2010
7	Voriconazole (Vfend)FDA LinkGeneric 04/2023 - 10/2013
7	Isoniazid (Ftivazide)FDA LinkGeneric 01/2022 - 08/2015
6	Streptomycin (Streptomycin Sulfate)FDA Link 01/2020 - 02/2010
6	VaccinesIBA 01/2019 - 05/2009
5	Moxifloxacin (Avelox)FDA Link 01/2022 - 06/2011
5	Levofloxacin (Levaquin)FDA Link 01/2019 - 10/2016
4	C-Reactive ProteinIBA 04/2023 - 12/2014
4	Clarithromycin (Biaxin)FDA LinkGeneric 01/2020 - 02/2010
4	posaconazole FDA Link 08/2019 - 10/2013
3	AcidsIBA 12/2023 - 06/2003
3	Pyrazinamide FDA LinkGeneric 01/2022 - 11/2018
3	Adrenal Cortex Hormones (Corticosteroids)IBA 08/2020 - 01/2003
3	EnzymesIBA 03/2019 - 09/2004
3	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 03/2019 - 12/2014
3	Carbapenems (Carbapenem Antibiotics)IBA 01/2019 - 04/2016
2	Biomarkers (Surrogate Marker)IBA 04/2022 - 01/2019
2	FluoroquinolonesIBA 01/2020 - 01/2018
2	Caspofungin (Cancidas)FDA Link 01/2020 - 01/2017
2	Glucose (Dextrose)FDA LinkGeneric 02/2019 - 01/2016
2	bedaquiline (R207910)IBA 01/2018 - 02/2016
2	NucleotidesIBA 01/2017 - 01/2014
2	AntigensIBA 01/2017 - 09/2004
2	Proteins (Proteins, Gene)FDA Link 01/2016 - 01/2011
2	Anidulafungin FDA Link 02/2015 - 01/2014
2	Sulfamethoxazole Drug Combination Trimethoprim (Co-Trimoxazole)FDA LinkGeneric 03/2014 - 08/2013
2	Indicators and Reagents (Reagents)IBA 02/2010 - 04/2009
2	CytokinesIBA 01/2005 - 09/2003
1	Ciprofloxacin (Cipro)FDA LinkGeneric 02/2023
1	SteroidsIBA 08/2020
1	Volatile Organic CompoundsIBA 08/2019
1	GoldIBA 01/2019
1	Darunavir (Prezista)FDA Link 01/2019
1	Ethambutol (Myambutol)FDA LinkGeneric 01/2019
1	Protease Inhibitors (Protease Inhibitor)IBA 01/2019
1	Clavulanic Acid (Potassium Clavulanate)FDA LinkGeneric 01/2019
1	Clofazimine (Lamprene)FDA Link 01/2018
1	Amikacin (A.M.K)FDA LinkGeneric 01/2018
1	Interferon Type IIBA 01/2017
1	Syntex adjuvant formulationIBA 01/2017
1	InflammasomesIBA 01/2017
1	OxidesIBA 01/2017
1	Type VII Secretion SystemsIBA 01/2017
1	Advanced Glycation End ProductsIBA 01/2017

Therapy/Procedure

10	Therapeutics 08/2020 - 07/2006
3	Aftercare (After-Treatment) 02/2023 - 07/2009
3	Duration of Therapy 01/2018 - 03/2014
3	Critical Care (Surgical Intensive Care) 03/2017 - 10/2008
2	Length of Stay 10/2017 - 03/2017
2	Injections 12/2016 - 03/2015
2	Enteral Nutrition (Feeding, Tube) 12/2015 - 09/2010
2	Debridement 01/2013 - 02/2010
1	Drug Tapering 01/2020
1	Electronic Nose 01/2019
1	Precision Medicine 10/2018
1	Pneumonectomy (Lung Volume Reduction) 01/2018